Classical Swine Fever (CSF)

Classical Swine Fever Virus (CSFV)

Classical Swine Fever (CSF), or Hog Cholera, is a highly contagious and often fatal viral disease of pigs caused by a Pestivirus in the Flaviviridae family. It affects domestic and wild pigs, with severe economic implications due to trade restrictions and control measures. CSF is a notifiable disease and must be reported immediately.

Transmission occurs through:

• Direct contact with infected animals
• Contaminated feed, fomites, and transport vehicles
• Feeding of uncooked swill or pork products

Clinical signs vary with virulence and may include:

• High fever, weakness, conjunctivitis
• Petechiae and cyanosis(ears, abdomen)
• Neurological signs, diarrhea, abortion, or stillbirths
• Sudden death in peracute forms

qPCR testing offers:

• Rapid, sensitive detection of CSFV RNA from blood, tonsils, spleen, lymph nodes, or oral fluids
• Early confirmation of infection, even before clinical signs are apparent
• Crucial support for disease surveillance, eradication programs, and movement control

qPCR is the gold standard diagnostic tool used by reference labs for:

• Outbreak investigation and control
• Pre-movement testing and certification
• Differentiation from African Swine Fever and other vesicular diseases

Early and accurate diagnosis helps prevent the spread of infection and limit economic losses through swift containment and regulatory action.